Complete Genome Sequence of the Apicomplexan, Cryptosporidium parvum
@article{Abrahamsen2004CompleteGS, title={Complete Genome Sequence of the Apicomplexan, Cryptosporidium parvum}, author={Mitchell S. Abrahamsen and Thomas J. Templeton and Shinichiro Enomoto and Juan E. Abrahante and Guan Zhu and Cheryl A. Lancto and Mingqi Deng and Chang Liu and Giovanni Widmer and Saul Tzipori and Gregory A. Buck and Ping Xu and A. T. Bankier and Paul H. Dear and Bernard A. Konfortov and H. Spriggs and Lakshminarayan M. Iyer and Vivek Anantharaman and L. Aravind and Vivek Kapur}, journal={Science}, year={2004}, volume={304}, pages={441 - 445} }
The apicomplexan Cryptosporidium parvum is an intestinal parasite that affects healthy humans and animals, and causes an unrelenting infection in immunocompromised individuals such as AIDS patients. We report the complete genome sequence of C. parvum, type II isolate. Genome analysis identifies extremely streamlined metabolic pathways and a reliance on the host for nutrients. In contrast to Plasmodium and Toxoplasma, the parasite lacks an apicoplast and its genome, and possesses a degenerate…
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