Complementation studies with Rous sarcoma virus gag and gag-pol polyprotein mutants.

@article{Oertle1992ComplementationSW,
  title={Complementation studies with Rous sarcoma virus gag and gag-pol polyprotein mutants.},
  author={Suzanne Oertle and Neil E. Bowles and Pierre F. Spahr},
  journal={Journal of virology},
  year={1992},
  volume={66 6},
  pages={
          3873-8
        }
}
Avian retroviruses (with the notable exception of spleen necrosis virus) express their protease (PR) both in their gag and their gag-pol polyprotein precursors, in contrast to other retroviruses, notably, the mammalian retroviruses, in which PR is encoded in the gag-pol polyprotein or in a separate reading frame as a gag-pro product. The consequence is that the avian PR is expressed in stoichiometric rather than catalytic amounts. To investigate the significance of the particular genome… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 12 REFERENCES

Overexpression of the gag - pol precursor from human immunodeficiency virus type 1 proviral genomes results in efficient proteolytic processing in the absence of virion production

  • R. B. Pepinsky, J. M. Vogt
  • J . Virol .
  • 1991

Role of the avian retroviral protease in the activation of reverse transcriptase during virion assembly

  • K. M. Felsenstein, S. P. Goff
  • J . Virol .
  • 1991

Retroviridae and their replication , p . 1437 - 1500

  • B. N. Fields, D. M. Knipe, R. C. Craven, R. P. Bennett, J. W. Wills
  • 1990

Production of single-stranded plasmid DNA.