Complementation by two non-homologous recombinant chromosomes 3.

  title={Complementation by two non-homologous recombinant chromosomes 3.},
  author={Penelope W Allderdice and Masood Ali and P. J. McAlpine},
  journal={American journal of medical genetics},
  volume={39 4},
The first example known to us of complementation by two non-homologous chromosomes 3 is present in the karyotype of a phenotypically normal brother of an inv(3)(p25q21) carrier. The normal chromosomes 3 are replaced by two complementary recombinant chromosomes 3. The longer recombinant duplicates 3q21-qter and is deficient for 3p25-pter. It is identical to the recombinant inherited by infants born with multiple congenital anomalies to inv(3)(p25q21) carriers. The shorter recombinant duplicates… CONTINUE READING


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