Complementary roles of grey matter MTR and T2 lesions in predicting progression in early PPMS.

@article{Tur2011ComplementaryRO,
  title={Complementary roles of grey matter MTR and T2 lesions in predicting progression in early PPMS.},
  author={C Tur and Z. Khaleeli and Olga Ciccarelli and Daniel R. Altmann and Mara Cercignani and David H. Miller and Alan J. Thompson},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={2011},
  volume={82 4},
  pages={423-8}
}
OBJECTIVE To investigate whether T2 lesion load and magnetisation transfer ratio (MTR) in the normal-appearing white matter (NAWM) and grey matter (GM) at study entry are independent predictors of progression and whether their changes correlate with the accrual of disability, over 5 years in early primary progressive multiple sclerosis (PPMS). METHODS Forty-seven patients with early PPMS and 18 healthy controls were recruited at baseline and invited to attend clinical 6-monthly assessments… CONTINUE READING