Complementary role of vasoactive intestinal polypeptide (VIP) and acetylcholine for cat submandibular gland blood flow and secretion. II. Effects of cholinergic antagonists and VIP antiserum.

@article{Lundberg1981ComplementaryRO,
  title={Complementary role of vasoactive intestinal polypeptide (VIP) and acetylcholine for cat submandibular gland blood flow and secretion. II. Effects of cholinergic antagonists and VIP antiserum.},
  author={Jan M. Lundberg and Anders Angg{\aa}rd and Jan Fahrenkrug},
  journal={Acta physiologica Scandinavica},
  year={1981},
  volume={113 3},
  pages={329-36}
}
The effects of atropine and hexamethonium on submandibular vasodilation, secretion and VIP release in response to parasympathetic nerve stimulation were studied in cats. It was found that salivary secretion was completely atropine sensitive at all frequencies. The vasodilatory response was characterized by an initial phase (most marked at lower frequencies) followed by a maintained phase (most pronounced at high frequencies). Atropine reduced the initial phase at all frequencies while the… CONTINUE READING
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