Complementary and Alternative Medicine for Atopic Dermatitis: An Evidence-Based Review

  title={Complementary and Alternative Medicine for Atopic Dermatitis: An Evidence-Based Review},
  author={Brittany L. Vieira and Neil R Lim and Mary E. Lohman and Peter A. Lio},
  journal={American Journal of Clinical Dermatology},
BackgroundComplementary and alternative interventions are becoming increasingly utilized as adjuncts to conventional treatment of atopic dermatitis (AD). While the number of studies continues to grow, the vastness of the subject coupled with the relatively poor quality and small size of the studies limit their usefulness to clinicians.PurposeOur aim was to comprehensively review randomized controlled trials (RCTs) of complementary and alternative therapies for AD.MethodsSearches were performed… 
Alternative Treatments for Atopic Dermatitis: An Update
The preliminary results for many treatments such as vitamin E, East Indian Sandalwood Oil (EISO), melatonin, l-histidine, and Manuka honey show positive clinical effects, but there is currently not enough evidence to recommend their use in AD therapy.
Complementary medicine and the role of integrative dermatology for the treatment of atopic dermatitis
A review of the literature showed promising complementary treatments for atopic dermatitis showed at least some level I evidence that supports the use of stressreducing techniques such as hypnosis, biofeedback and massage, balneotherapy, herbal products, botanical oils, oral evening primrose oil, vitamin B12 and D, acupuncture, and acupressure.
Assessment of the Effectiveness of Vitamin Supplement in Treating Eczema: A Systematic Review and Meta-Analysis
It is suggested that vitamin supplements could be important therapeutics to help manage eczema patients.
Use of Complementary and Alternative Therapies in Outpatients with Atopic Dermatitis from a Dermatological University Department
The high prevalence of CAM may indicate that patients’ expectations regarding treatment of AD are not redeemed in the conventional health care system, and CAM users are characterized by long disease duration, a significant disease burden and by having a longer education.
A clinician's reference guide for the management of atopic dermatitis in Asians
The management of AD among Asians requires a holistic approach, integrating evidence-based treatments while considering accessibility and cultural acceptability.
Complementary and Alternative Treatment Methods Practiced by Parents in Pediatric Cases Diagnosed with Atopic Dermatitis.
CATs are widely used in AD and Physicians should know the socio-cultural structure of the region they are in, the CATs used and their side effects, and inform the families.
Quality assessment of atopic dermatitis clinical practice guidelines in ≤ 18 years
It is suggested that future atopic dermatitis CPGs should emphasize in the facilitating factors and barriers that may influence the application of guideline recommendations.
Integrative Skin Care: Dermatology and Traditional and Complementary Medicine.
An overview of current knowledge about traditional and complementary medicine (T&CM) and IM principles and practices for skin health is presented; published epidemiologic studies, clinical trials, and wider literature are reviewed; and the challenges of conducting research into T&CM and IM are discussed.
What's new in atopic eczema? An analysis of systematic reviews published in 2016. Part 1: treatment and prevention
There is evidence that topical corticosteroids and calcineurin inhibitors have similar efficacy and that both can prevent AE flares when used twice weekly as maintenance therapy, however, topical calcineURin inhibitors are costlier and have more adverse reactions, thus topical cortICosteroids should remain the standard of care for patients with AE.


Atopic Dermatitis: An Evidence-Based Treatment Update
  • J. Silverberg
  • Medicine
    American Journal of Clinical Dermatology
  • 2014
Investigator-initiated RCTs support the use of the systemic agents cyclosporine, methotrexate, azathioprine and mycophenolate mofetil, and in one RCT, petrolatum was found to be as effective as creams containing ceramides or glycyrrhetinic acid.
Complementary and alternative interventions in atopic dermatitis.
Dietary supplements for established atopic eczema.
There is no convincing evidence of the benefit of dietary supplements in eczema, and they cannot be recommended for the public or for clinical practice at present.
Efficacy of traditional Chinese herbal therapy in adult atopic dermatitis
Therapeutic effect and safety of a traditional Chinese medicine for atopic dermatitis in children: a randomised, double-blind, placebo-controlled study.
The formulation was based on a widely used traditional concoction, with no corticosteroid or related compound, and the therapeutic efficacy, tolerability, and safety of this concoction in children with AD was determined.
Evening primrose oil is effective in atopic dermatitis: a randomized placebo-controlled trial.
BACKGROUND Atopic dermatitis (AD) is a chronic, relapsing, itchy dermatosis of multifactorial origin, which commonly starts in childhood. Defective metabolism of essential fatty acids leading to
The use of alternative or complementary medicine for children with atopic dermatitis.
Phytotherapy and homeopathy were the most used therapies for pediatric patients with atopic dermatitis at the University Hospital of Brasília in the period between March 2007 and December 2008.
Efficacy and Safety of a Traditional Herbal Medicine, Hochu-ekki-to in the Long-term Management of Kikyo (Delicate Constitution) Patients with Atopic Dermatitis: A 6-month, Multicenter, Double-blind, Randomized, Placebo-controlled Study
It is demonstrated that Hochu-ekki-to is a useful adjunct to conventional treatments for AD patients with Kikyo constitution, and significantly reduces the dose of topical steroids and/or tacrolimus used for AD treatment without aggravating AD.
Effectiveness of Acupressure on Pruritus and Lichenification Associated with Atopic Dermatitis: A Pilot Trial
Background Pruritus is a debilitating aspect of atopic dermatitis (AD). Acupuncture has been reported to diminish pruritus, but self-administered acupressure has not been previously evaluated.