Complementary Role of Fibroblast Growth Factor 21 and Cytokeratin 18 in Monitoring the Different Stages of Nonalcoholic Fatty Liver Disease

@inproceedings{Wu2017ComplementaryRO,
  title={Complementary Role of Fibroblast Growth Factor 21 and Cytokeratin 18 in Monitoring the Different Stages of Nonalcoholic Fatty Liver Disease},
  author={Guangyu Wu and Huating Li and Qichen Fang and Jing Zhang and Mingliang Zhang and Lei Zhang and Liang Wu and Xuhong Hou and Junxi Lu and Yuqian Bao and Weiping Jia},
  booktitle={Scientific Reports},
  year={2017}
}
Fibroblast growth factor 21 (FGF21) and cytokeratin 18 (CK18) were previously reported to be elevated in nonalcoholic fatty liver disease (NAFLD). We aim to analyze the differential roles of FGF21, cell apoptosis marker CK18 fragment M30 and total cell death marker CK18 M65ED in monitoring the different stages of NAFLD spectrum in a population-based prospective cohort comprising 808 Chinese subjects. Predictive performances for monitoring the different stages of NAFLD were assessed by logistic… CONTINUE READING
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