Complementary DNA sequencing: expressed sequence tags and human genome project

@article{Adams1991ComplementaryDS,
  title={Complementary DNA sequencing: expressed sequence tags and human genome project},
  author={Mark Adams and Jm Kelley and J. D. Gocayne and Mark Dubnick and M. M. Polymeropoulos and H. Xiao and CR Merril and And Wu and Björn Olde and RF Moreno and al. et},
  journal={Science},
  year={1991},
  volume={252},
  pages={1651 - 1656}
}
Automated partial DNA sequencing was conducted on more than 600 randomly selected human brain complementary DNA (cDNA) clones to generate expressed sequence tags (ESTs). ESTs have applications in the discovery of new human genes, mapping of the human genome, and identification of coding regions in genomic sequences. Of the sequences generated, 337 represent new genes, including 48 with significant similarity to genes from other organisms, such as a yeast RNA polymerase II subunit; Drosophila… Expand
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