Complement the hemostatic system: an intimate relationship.

  title={Complement the hemostatic system: an intimate relationship.},
  author={Ilene Ceil Weitz},
  journal={Thrombosis research},
  volume={133 Suppl 2},
The complement system is important part of our innate immune system and interacts directly with the hemostatic system. Disorders of complement activation or dysregulation resulting in excess complement generation, such as Paroxysmal Nocturnal Hemoglobinuria (PNH), atypical Hemolytic uremic Syndrome (aHUS) and antiphospholipid syndrome (APLS) have been associated with significant thrombophilia. Terminal Complement (C5b-9) deposition on endothelial and tumor cell membranes has also been reported… CONTINUE READING
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