Complement opsonization of HIV-1 results in a different intracellular processing pattern and enhanced MHC class I presentation by dendritic cells

@inproceedings{Tjomsland2013ComplementOO,
  title={Complement opsonization of HIV-1 results in a different intracellular processing pattern and enhanced MHC class I presentation by dendritic cells},
  author={Veronica Tjomsland and Rada Elleg{\aa}rd and Adam D Burgener and Kenzie Mogk and Karlhans Fru Che and Garrett R. Westmacott and Jorma Hinkula and Jeffrey D Lifson and Marie Louise Larsson},
  booktitle={European journal of immunology},
  year={2013}
}
Induction of optimal HIV-1-specific T-cell responses, which can contribute to controlling viral infection in vivo, depends on antigen processing and presentation processes occurring in DCs. Opsonization can influence the routing of antigen processing and pathways used for presentation. We studied antigen proteolysis and the role of endocytic receptors in MHC class I (MHCI) and II (MHCII) presentation of antigens derived from HIV-1 in human monocyte-derived immature DCs (IDCs) and mature DCs… CONTINUE READING
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SHOWING 1-10 OF 45 REFERENCES

The genotype of early-transmitting HIV gp120s promotes alpha (4) beta(7)-reactivity, revealing alpha

F. Nawaz, C. Cicala, +4 authors O Ogundare
  • PLoS Pathog. 2011
  • 2011