Complement modulates the cutaneous microbiome and inflammatory milieu.


The skin is colonized by a plethora of microbes that include commensals and potential pathogens, but it is currently unknown how cutaneous host immune mechanisms influence the composition, diversity, and quantity of the skin microbiota. Here we reveal an interactive role for complement in cutaneous host-microbiome interactions. Inhibiting signaling of the… (More)
DOI: 10.1073/pnas.1307855110


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@article{Chehoud2013ComplementMT, title={Complement modulates the cutaneous microbiome and inflammatory milieu.}, author={Christel Chehoud and Stavros S. Rafail and Amanda S. Tyldsley and John T Seykora and John D. Lambris and Elizabeth A Grice}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2013}, volume={110 37}, pages={15061-6} }