Complement-mediated inhibition of adiponectin regulates perivascular inflammation and vascular injury in hypertension.


Perivascular adipose tissue (PVAT)-derived adiponectin (APN) is a secreted adipokine that protects against hypertension-related cardiovascular injury. However, the regulation of APN expression in hypertension remains to be explored. In this study, we demonstrated that down-regulation of APN was associated with complement activation in the PVAT of… (More)
DOI: 10.1096/fj.201600780R


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