Complement factors c3a, c4a, and c5a in chronic obstructive pulmonary disease and asthma.

@article{Marc2004ComplementFC,
  title={Complement factors c3a, c4a, and c5a in chronic obstructive pulmonary disease and asthma.},
  author={Mateja M Marc and P Koro{\vs}ec and Mitja Ko{\vs}nik and Izidor Kern and Matjaz Flezar and Stanislav Suskovic and Jurij Sorli},
  journal={American journal of respiratory cell and molecular biology},
  year={2004},
  volume={31 2},
  pages={216-9}
}
Studies of animal models have shown that the activation of the complement system could have a role in chronic obstructive pulmonary disease (COPD) and asthma by promoting inflammation and enhancing airway hyperresponsiveness. We sought to determine whether the levels of complement factors C3a, C4a, and C5a are elevated at the site of inflammation in patients with COPD and patients with asthma. We analyzed the induced sputum of seven patients with COPD, ten patients with asthma, and twelve… CONTINUE READING
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