Complement factor C5a and epidermal growth factor trigger the activation of outward potassium currents in cultured murine microglia.

Abstract

Microglia, the resident macrophages of the brain, are transformed from a quiescent into an activated phenotype in a number of pathological conditions. The signalling mechanisms which control such transformations are not yet understood. In the present study, we have characterized fast electrophysiological responses in cultured microglia, induced by two… (More)

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