Complement evasion by Echinococcus granulosus: sequestration of host factor H in the hydatid cyst wall.

@article{Diaz1997ComplementEB,
  title={Complement evasion by Echinococcus granulosus: sequestration of host factor H in the hydatid cyst wall.},
  author={Alvaro Diaz and Ana Mar{\'i}a Ferreira and Robert B Sim},
  journal={Journal of immunology},
  year={1997},
  volume={158 8},
  pages={3779-86}
}
Hydatid disease, which affects humans and various livestock species, is caused by the larval stages of the cestode parasite Echinococcus granulosus. The disease involves the growth of a fluid-filled cyst in the host's internal organs. The hydatid cyst wall is generally thought to preclude the access of host immune cells to the cyst, while allowing passage of macromolecules. Thus, evasion of humoral effector mechanisms, in particular the complement system, may be crucial to parasite survival… CONTINUE READING

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