Complement deposition in renal histopathology of patients with ANCA-associated pauci-immune glomerulonephritis.

@article{Chen2008ComplementDI,
  title={Complement deposition in renal histopathology of patients with ANCA-associated pauci-immune glomerulonephritis.},
  author={Min Chen and Guang-qun Xing and Feng Yu and Gang Liu and Ming-hui Zhao},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={2008},
  volume={24 4},
  pages={
          1247-52
        }
}
BACKGROUND The pathogenesis of ANCA-associated pauci-immune glomerulonephritis has not been fully elucidated. Several studies had suggested that complement deposition could be detected in renal histopathology. The current study investigated the clinical and pathological significance of complement deposition in renal histopathology of patients with ANCA-associated pauci-immune glomerulonephritis. METHODS Renal biopsy specimens from 112 patients with ANCA-associated pauci-immune… CONTINUE READING

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Glomerular immune deposits are associated with increased proteinuria in patients with ANCA-associated crescentic nephritis.

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