Complement activation in primiparous women from a malaria endemic area is associated with reduced birthweight.

@article{Khattab2013ComplementAI,
  title={Complement activation in primiparous women from a malaria endemic area is associated with reduced birthweight.},
  author={A. Nabil Khattab and Peter Gottfried Kremsner and Seppo Meri},
  journal={Placenta},
  year={2013},
  volume={34 2},
  pages={162-7}
}
The hallmark of placental malaria (PM) due to Plasmodium falciparum infection is the accumulation of mature-stage parasites, monocytes and macrophages in the maternal vascular bed of the placenta. The mechanisms leading to morbidity and mortality in PM are incompletely understood. However, an inflammatory response in the placenta has been related to both severe anemia in the mother and low birthweight (<2500 g) in the newborn. In this study we analyzed whether complement activation as a… CONTINUE READING

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