Complement activation, regulation, and molecular basis for complement-related diseases.

Abstract

The complement system is an essential element of the innate immune response that becomes activated upon recognition of molecular patterns associated with microorganisms, abnormal host cells, and modified molecules in the extracellular environment. The resulting proteolytic cascade tags the complement activator for elimination and elicits a pro-inflammatory… (More)
DOI: 10.15252/embj.201591881

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Cite this paper

@article{Bajic2015ComplementAR, title={Complement activation, regulation, and molecular basis for complement-related diseases.}, author={Goran Bajic and S E Degn and Steffen Thiel and Gregers Rom Andersen}, journal={The EMBO journal}, year={2015}, volume={34 22}, pages={2735-57} }