Complement Regulates Nu trient Influx and Metabolic Reprogramming during Th 1 Cell

@inproceedings{Kolev2015ComplementRN,
  title={Complement Regulates Nu trient Influx and Metabolic Reprogramming during Th 1 Cell},
  author={Martin Kolev and Sarah Dimeloe and Gaelle Le Friec and Alexander Navarini and Giuseppina Arbore and Giovanni A M Povoleri and Marco Fischer and R{\'e}ka Belle and Jordan Loeliger and Leyla Develioglu and Glenn Robert Bantug and Julie D Watson and Lionel Couzi and Behdad Afzali and Paul Lavender and Christoph Hess and Claudia Kemper},
  year={2015}
}
Graphical Abstract Highlights d CD46 regulates GLUT1 and LAT1 and enhances glucose and AA uptake in T cells d LAMTOR5 mediates Ragulator-Rag-mTORC1 assembly in activated T cells d Complement drives glycolysis and oxidative phosphorylation critical to Th1 cell induction In Brief The in vivo signals that drive metabolic reprograming of activated T cells… CONTINUE READING