Competitive protein adsorption on polysaccharide and hyaluronate modified surfaces.

@article{Ombelli2011CompetitivePA,
  title={Competitive protein adsorption on polysaccharide and hyaluronate modified surfaces.},
  author={Michela Ombelli and Lauren N. Costello and Corinne Postle and Vinod Anantharaman and Qing Cheng Meng and Russell J Composto and David M. Eckmann},
  journal={Biofouling},
  year={2011},
  volume={27 5},
  pages={
          505-18
        }
}
Adsorption of bovine serum albumin (BSA) and fibrinogen (Fg) was measured on six distinct bare and dextran- and hyaluronate-modified silicon surfaces created using two dextran grafting densities and three hyaluronic acid (HA) sodium salts derived from human umbilical cord, rooster comb and Streptococcus zooepidemicus. Film thickness and surface morphology depended on the HA molecular weight and concentration. BSA coverage was enhanced on surfaces in competitive adsorption of BSA:Fg mixtures… CONTINUE READING
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