Competitive nephelometric immunoassay of theophylline in plasma.


We have developed an accurate, simple, and rapid method for the determination of theophylline in plasma. The principle of the method is based on inhibition of immunoprecipitation by hapten. A nephelometer is used to measure the scattered light from the immunoprecipitate. The macromolecule, which possesses numerous theophylline moieties and forms… (More)


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