Competitive nature of the intestinal transport mechanism for cobalt and iron in the rat.

@article{Thomson1971CompetitiveNO,
  title={Competitive nature of the intestinal transport mechanism for cobalt and iron in the rat.},
  author={Alan B. R. Thomson and Leslie S Valberg and Dr. G. Malcolm Sinclair},
  journal={The Journal of clinical investigation},
  year={1971},
  volume={50 11},
  pages={2384-94}
}
Dose- and time-response studies were performed in iron-loaded and iron-deficient rats in order to define, (a) the kinetics of absorption of cobalt and iron, (b) the nature of the inhibitory effect of one metal on the absorption of the other, and (c) the effect of variations in body iron stores on these processes. The duodenum was perfused for 5-90 min with labeled solutions containing 5.0 mM iron or 5.0 mM cobalt. In iron-loaded rats, the rate of cobalt absorption was constant for 90 min… CONTINUE READING

From This Paper

Figures and tables from this paper.

References

Publications referenced by this paper.
Showing 1-4 of 4 references

Effect of varying iron stores on the site of intestinal absorption of cobalt and iron

  • B. E. Glader
  • Amer . J . Physiol .
  • 1970

Similar Papers

Loading similar papers…