Competing crossover pathways act during meiosis in Saccharomyces cerevisiae.

  title={Competing crossover pathways act during meiosis in Saccharomyces cerevisiae.},
  author={Juan Lucas Argueso and Jennifer J Wanat and Zekeriyya Gemici and Eric Alani},
  volume={168 4},
In Saccharomyces cerevisiae the MSH4-MSH5, MLH1-MLH3, and MUS81-MMS4 complexes act to promote crossing over during meiosis. MSH4-MSH5, but not MUS81-MMS4, promotes crossovers that display interference. A role for MLH1-MLH3 in crossover control is less clear partly because mlh1Delta mutants retain crossover interference yet display a decrease in crossing over that is only slightly less severe than that seen in msh4Delta and msh5Delta mutants. We analyzed the effects of msh5Delta, mlh1Delta, and… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.
69 Citations
15 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 69 extracted citations


Publications referenced by this paper.
Showing 1-10 of 15 references

Zip 2 , a meiosisspecific protein DNA double - strand breaks are catalyzed by Spo 11 , a member of a widely conserved protein family

  • G. S. Roeder
  • Meiosis - specific
  • 1998
2 Excerpts

Saccharomyces cerevisiae Mer 3 helicase 1999 Mammalian MutS homologue 5 is required for chromosome pairing in meiosis

  • R. Egel
  • Nat . Genet . Cell
  • 1995
1 Excerpt

Genetic Crossover interference in Saccharomyces cerevisiae requires a TID 1 / and physical maps of Saccharomyces cerevisiae , ed . 11

  • R. K. Mortimer
  • Genetics
  • 1992

Functional overlap between Sgs 1Top 3

  • A. T. Carpenter
  • 1987
1 Excerpt

Similar Papers

Loading similar papers…