Competence for transformation: a matter of taste.

  title={Competence for transformation: a matter of taste.},
  author={Pablo Tortosa and David Dubnau},
  journal={Current opinion in microbiology},
  volume={2 6},
Genetic competence in both Bacillus subtilis and Streptococcus pneumoniae, as well as virulence in Staphylococcus aureus, are regulated by quorum-sensing mechanisms that use two-component signal transduction systems to respond to extracellular peptide pheromones. Recent data indicate that in all three systems closely related strains express markedly different pheromones and polytopic membrane receptor proteins. This polymorphism may function as a sexual isolation mechanism. In B. subtilis the… CONTINUE READING

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