Competence for natural transformation in Neisseria gonorrhoeae: components of DNA binding and uptake linked to type IV pilus expression

@article{Aas2002CompetenceFN,
  title={Competence for natural transformation in Neisseria gonorrhoeae: components of DNA binding and uptake linked to type IV pilus expression},
  author={F. E. Aas and M. Wolfgang and S. Frye and S. Dunham and Cecilia L{\o}vold and M. Koomey},
  journal={Molecular Microbiology},
  year={2002},
  volume={46}
}
The mechanisms by which DNA is taken up into the bacterial cell during natural genetic transformation are poorly understood. Although related components essential to the uptake of DNA during transforma‐tion have been defined in Gram‐negative species, it remains unclear whether DNA binding and uptake are dissociable events. Therefore, DNA uptake has been the earliest definable step in any Gram‐negative transformation pathway. In the human pathogen Neisseria gonorrhoeae, sequence‐specific DNA… Expand
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