Compensatory branching morphogenesis of stalk cells in the Drosophila trachea.

@article{Francis2015CompensatoryBM,
  title={Compensatory branching morphogenesis of stalk cells in the Drosophila trachea.},
  author={Deanne Francis and Amin S Ghabrial},
  journal={Development},
  year={2015},
  volume={142 11},
  pages={
          2048-57
        }
}
Tubes are essential for nutrient transport and gas exchange in multicellular eukaryotes, but how connections between different tube types are maintained over time is unknown. In the Drosophila tracheal system, mutations in oak gall (okg) and conjoined (cnj) confer identical defects, including late onset blockage near the terminal cell-stalk cell junction and the ectopic extension of autocellular, seamed tubes into the terminal cell. We determined that okg and cnj encode the E and G subunits of… CONTINUE READING
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