Compensatory Feto-Placental Upregulation of the Nitric Oxide System during Fetal Growth Restriction

@inproceedings{Pisaneschi2012CompensatoryFU,
  title={Compensatory Feto-Placental Upregulation of the Nitric Oxide System during Fetal Growth Restriction},
  author={Silvia Pisaneschi and Francesca Letizia Strigini and Angel Mat{\'i}as Sanchez and Silvia Begliuomini and Elena Casarosa and Andrea Ripoli and Paolo Ghirri and Antonio Boldrini and Bruno Fink and Andrea Riccardo Genazzani and Flavio Coceani and Tommaso Simoncini},
  booktitle={PloS one},
  year={2012}
}
BACKGROUND Fetal Growth Restriction is often associated with a feto-placental vascular dysfunction conceivably involving endothelial cells. Our study aimed to verify this pathogenic role for feto-placental endothelial cells and, coincidentally, demonstrate any abnormality in the nitric oxide system. METHODS Prenatal assessment of feto-placental vascular function was combined with measurement of nitric oxide (in the form of S-nitrosohemoglobin) and its nitrite byproduct, and of the endogenous… CONTINUE READING