Compatibility of common additives in protein hydrolysate/dextrose solutions.

@article{Kobayashi1977CompatibilityOC,
  title={Compatibility of common additives in protein hydrolysate/dextrose solutions.},
  author={Noritaka Kobayashi and J C King},
  journal={American journal of hospital pharmacy},
  year={1977},
  volume={34 6},
  pages={
          589-94
        }
}
The compatibility of common additives in protein hydrolysate/dextrose solutions was studied. The additives included electrolytes (calcium gluconate, potassium phosphate and magnesium sulfate), vitamins (M.V.I., Solu B Forte, phytonadione, cyanocobalamin and folic acid), insulin and heparin sodium. Various concentrations of the admixtures were observed at intervals throughout a 24-hour period. Combinations which displayed no physical change were subjected to spectrophotometric analysis. Thin… 
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18 Citations

18 Citations

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Citation Type

The solubility of calcium and phosphorus in neonatal total parenteral nutrition solutions.
TLDR
Calcium and phosphate compatibility in commonly used neonatal TPN solutions containing a final concentration of either 1 or 2% amino acids was determined to allow pharmacists to avoid compounding TPN Solutions that will precipitate, thus saving considerable cost to the pharmacy and preventing complications.
Stability of folic acid in 25% dextrose, 3.5% amino acids, and multivitamin solution.
TLDR
Folic acid admixed in the study solution is chemically stable for up to 48 hr after initial admixture under normal total parenteral nutrition storage conditions and stability was found to be independent of temperature or light storage effects.
COMPATIBILITY AND STABILITY OF TPN MIXTURES IN BIG BAGS
  • M. Allwood
  • Medicine
    Journal of clinical and hospital pharmacy
  • 1984
TLDR
The mixing of all the ingredients necessary for 24-h total parenteral nutrition (TI) into a larger, usually 1 or 3 litre capacity, flexible container or 'Big Bag' is now rapidly becoming accepted as the safest and most convenient method of T P N administration.
Chemical stability of total parenteral nutrition mixtures
Stability of total parenteral nutrition supplied as ‘all-in-one’ for children with chemotherapy-linked hyperhydration
TLDR
The maximal allowable concentrations of calcium and phosphate in total parenteral nutrition mixtures for children from one compartment were investigated and the stability of the fat emulsion was visually assessed and the particle size distribution was measured by flow cytometry.
Calcium and phosphorus solubility in neonatal intravenous feeding solutions.
TLDR
The solubility limits of calcium and phosphorus were determined by increasing the concentrations of dextrose, amino acids, and by using Addiphos instead of 8.7% dipotassium hydrogen phosphate as the phosphorus source, to permit the delivery of increased concentrations of these minerals at rates which approximate fetal accretion.
Calcium phosphate crystal occlusion of central venous catheters used for total parenteral nutrition in infants and children: prevention and treatment.
STORAGE OF MIXTURES FOR TOTAL PARENTERAL NUTRITION III. STABILITY OF VITAMINS IN TPN MIXTURES
TPN mixtures should contain all nutritional element necessary in the nutritional therapy—including unstable vitamins.
Pulmonary deposition of calcium phosphate crystals as a complication of home total parenteral nutrition.
A patient on home total parenteral nutrition (TPN) developed a diffuse granulomatous interstitial pneumonitis secondary to calcium phosphate deposition. Calcium and phosphorus concentrations in the…
Incompatibility between Calcium and Sulfate Ions in Solutions for Injection
Objective: To investigate the potential physical compatibility of magnesium sulfate injection with calcium‐containing injections in various infusion solutions and to demonstrate that gross visual…
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