• Corpus ID: 212489295

Compatibility and stability studies of levadopa, carbidopa, entacapone and natural bioenhancer mixture

  title={Compatibility and stability studies of levadopa, carbidopa, entacapone and natural bioenhancer mixture},
  author={R. Dhawan and Dr. S. Ravi and Dr. T. Subburaju},
Levodopa, Carbidopa and Entacapone are used for the treatment of Parkinsonism disease. Piperine is an alkaloid from Piper species is reported to enhance the oral bioavailability of co-administered drugs. Piperine can improve the bioavailability of Levodopa in solid oral dosage forms. The present study was aimed to added Piperine natural bio-enhancer as a formulation additive in oral formulations of Levodopa, Carbidopa and Entacapone. The physical mixture of Levodopa, Carbidopa, Entacapone and… 



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  • Parkinson's Disease. London: Royal College of Physicians. Edition
  • 2006