Compartmentalized expression of Th1 and Th17 cytokines in pediatric inflammatory bowel diseases.

@article{Verdier2012CompartmentalizedEO,
  title={Compartmentalized expression of Th1 and Th17 cytokines in pediatric inflammatory bowel diseases.},
  author={Julien Verdier and Bernadette B{\`e}gue and Nadine Cerf-Bensussan and Frank M. Ruemmele},
  journal={Inflammatory bowel diseases},
  year={2012},
  volume={18 7},
  pages={
          1260-6
        }
}
BACKGROUND Interleukin (IL)-23, IL-17A, IL-17F, and interferon-gamma (IFN-γ) are important mediators of inflammatory colitis and are potential therapeutic targets in inflammatory bowel disease (IBD). Their expression profile in the different parts of normal noninflammatory intestine is unclear and their changes during pathology have not yet been addressed in pediatric IBD patients. METHODS We quantified the transcriptional expression of IL-23, IL-12, IL-17A, IL-17F, IL-6, and IL-10 in healthy… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

Host response mechanisms in periodontal diseases

Journal of applied oral science : revista FOB • 2015

Similar Papers

Loading similar papers…