Compartmentalized cytokine production within the human lung in unilateral pneumonia.

  title={Compartmentalized cytokine production within the human lung in unilateral pneumonia.},
  author={Monique Dehoux and Anne Boutten and Juliette Ostinelli and Noriyuki Seta and Marie Christine Dombret and Bruno Crestani and Martin Deschenes and Jean Louis Trouillet and Michel Aubier},
  journal={American journal of respiratory and critical care medicine},
  volume={150 3},
The in situ inflammatory response developing in the human lung during a localized bacterial infection was studied in 15 patients with unilateral community-acquired pneumonia (CAP). The local response in the involved lung was compared with that in the contralateral, noninvolved lung as well as with the systemic blood response. Eight healthy volunteers served as control subjects. Concentrations of tumor necrosis factor-alpha (TNF-alpha), interleukin-1 beta (IL-1 beta), and interleukin-6 (IL-6… CONTINUE READING


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