Compartmentalized Eph receptor and ephrin expression in the thymus.

  title={Compartmentalized Eph receptor and ephrin expression in the thymus.},
  author={Andrea Vergara-Silva and Katherine L. Schaefer and Leslie J Berg},
  journal={Mechanisms of development},
  volume={119 Suppl 1},
The maturation of T cells is an intricate process involving the interaction of developing thymocytes with discrete microenvironments within the thymus. Numerous studies have indicated that distinct thymic compartments provide signals required for each stage of thymocyte maturation. In this study we performed a comprehensive analysis of the expression patterns of Eph-A receptors and ephrins-A in the thymus using in situ hybridization and reverse transcription-polymerase chain reaction, and show… CONTINUE READING


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