Compartmentalization of specific pre-mRNA metabolism: an emerging view.

  title={Compartmentalization of specific pre-mRNA metabolism: an emerging view.},
  author={Phillip T. Moen and Kelly P. Smith and J B Lawrence},
  journal={Human molecular genetics},
  volume={4 Spec No},
It is increasingly recognized that the mammalian interphase nucleus contains a number of non-membranous compartments in which macromolecules associated with different nuclear functions concentrate. This review focuses on the function of a major compartment consisting of domains highly enriched in pre-mRNA splicing components and poly (A) RNA, commonly identified by the splicing factor, SC-35. RNA synthesis, as judged interdomain space. However, uridine labels several types of nuclear RNA, only… CONTINUE READING

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