Compartmentalization of proteins in lipid droplet biogenesis.


Our existing understanding of the structure, protein organization and biogenesis of the lipid droplet has relied heavily on microscopical techniques that lack resolution and the ability to preserve native cellular and protein composition. The electron microscopic technique of freeze-fracture replica immunogold labeling (FRIL) overcomes these problems, and… (More)
DOI: 10.1016/j.bbalip.2008.12.001