Compartmentalization of endoplasmic reticulum quality control and ER-associated degradation factors.

@article{Leitman2013CompartmentalizationOE,
  title={Compartmentalization of endoplasmic reticulum quality control and ER-associated degradation factors.},
  author={Julia Leitman and Efrat Ron and Navit Ogen-Shtern and Gerardo Zelmar Lederkremer},
  journal={DNA and cell biology},
  year={2013},
  volume={32 1},
  pages={
          2-7
        }
}
Recent studies are delineating a detailed picture of the architecture and function of the endoplasmic reticulum (ER) and the early secretory pathway, showing the existence of dynamic compartmentalization of ER quality control and ER-associated degradation (ERAD) factors. The compartmentalization is regulated by ER protein load and in turn regulates protein processing and cell fate. This compartmentalization is intimately linked to the protein quality control processes, protein disposal through… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 14 CITATIONS

Palmitoylation is the switch that assigns calnexin to quality control or ER Ca2+ signaling.

  • Journal of cell science
  • 2013
VIEW 10 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 68 REFERENCES

ERp57, a multifunctional endoplasmic reticulum resident oxidoreductase.

  • The international journal of biochemistry & cell biology
  • 2010
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL