Compartmentalization of acute phase reactants Interleukin-6, C-Reactive Protein and Procalcitonin as biomarkers of intra-amniotic infection and chorioamnionitis.

@article{Dulay2015CompartmentalizationOA,
  title={Compartmentalization of acute phase reactants Interleukin-6, C-Reactive Protein and Procalcitonin as biomarkers of intra-amniotic infection and chorioamnionitis.},
  author={Antonette T. Dulay and Irina Alexandra Buhimschi and Guomao Zhao and Mert Ozan Bahtiyar and Stephen F. Thung and Michael Cackovic and Catalin Sorin Buhimschi},
  journal={Cytokine},
  year={2015},
  volume={76 2},
  pages={
          236-243
        }
}
BACKGROUND The arsenal of maternal and amniotic fluid (AF) immune response to local or systemic infection includes among others the acute-phase reactants IL-6, C-Reactive Protein (CRP) and Procalcitonin (PCT). If these molecules can be used as non-invasive biomarkers of intra-amniotic infection (IAI) in the subclinical phase of the disease remains incompletely known. METHODS We used time-matched maternal serum, urine and AF from 100 pregnant women who had an amniocentesis to rule out IAI in… CONTINUE READING
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