Compartmentalization of Ras proteins.

@article{Prior2001CompartmentalizationOR,
  title={Compartmentalization of Ras proteins.},
  author={Ian A Prior and John F Hancock},
  journal={Journal of cell science},
  year={2001},
  volume={114 Pt 9},
  pages={
          1603-8
        }
}
The Ras GTPases operate as molecular switches that link extracellular stimuli with a diverse range of biological outcomes. Although many studies have concentrated on the protein-protein interactions within the complex signaling cascades regulated by Ras, it is becoming clear that the spatial orientation of different Ras isoforms within the plasma membrane is also critical for their function. H-Ras, N-Ras and K-Ras use different membrane anchors to attach to the plasma membrane. Recently it has… CONTINUE READING

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