Corpus ID: 46601484

Compartmentalization of Ras proteins.

  title={Compartmentalization of Ras proteins.},
  author={I. Prior and J. Hancock},
  journal={Journal of cell science},
  volume={114 Pt 9},
  • I. Prior, J. Hancock
  • Published 2001
  • Biology, Medicine
  • Journal of cell science
  • The Ras GTPases operate as molecular switches that link extracellular stimuli with a diverse range of biological outcomes. Although many studies have concentrated on the protein-protein interactions within the complex signaling cascades regulated by Ras, it is becoming clear that the spatial orientation of different Ras isoforms within the plasma membrane is also critical for their function. H-Ras, N-Ras and K-Ras use different membrane anchors to attach to the plasma membrane. Recently it has… CONTINUE READING
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