Compartmentalised depletion of glutathione in cells treated with buthionine sulphoximine.

@article{Edgren1987CompartmentalisedDO,
  title={Compartmentalised depletion of glutathione in cells treated with buthionine sulphoximine.},
  author={M. Edgren and L. R{\'e}v{\'e}sz},
  journal={The British journal of radiology},
  year={1987},
  volume={60 715},
  pages={
          723-4
        }
}
Evidence obtained in different types of experiments has indicated that glutathione (GSH) can function as an inherent protector of cells against treatment with radiation and many chemotherapeutic agents (Arrick & Nathan, 1984). In an attempt to enhance the effect of such treatments, efforts have been made to control the cellular GSH content artificially. In many of the recent studies, buthionine sulphoximine (BSO) has been used to deplete cellular GSH (Chemical Modifiers of Cancer Treatment… Expand
Extracellular: intracellular and subcellular concentration gradients of thiols.
...
1
2
3
4
...

References

SHOWING 1-4 OF 4 REFERENCES
Nuclear glutathione and oxygen enhancement of radiosensitivity.
  • M. Edgren
  • Chemistry, Medicine
  • International journal of radiation biology and related studies in physics, chemistry, and medicine
  • 1987