Compartment-specific modulation of GABAergic synaptic transmission by mu-opioid receptor in the mouse striatum with green fluorescent protein-expressing dopamine islands.

@article{Miura2007CompartmentspecificMO,
  title={Compartment-specific modulation of GABAergic synaptic transmission by mu-opioid receptor in the mouse striatum with green fluorescent protein-expressing dopamine islands.},
  author={Masami Miura and Sachiko Saino-Saito and Masao Masuda and Kazuto Kobayashi and Toshihiko Aosaki},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2007},
  volume={27 36},
  pages={9721-8}
}
The striatum is a heterogeneous mosaic of two neurochemically, developmentally, and functionally distinct compartments: the mu-opioid receptor (MOR)-enriched striosomes and the matrix. Preferential activation of the striosomes and persistent suppression of the matrix have recently been suggested to represent neural correlates of motor stereotypy. However, little is known concerning the physiological properties of the striosomes. We made patch-clamp recordings from medium spiny neurons in… CONTINUE READING

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