Comparisons of peak diurnal expiratory flow variation, postbronchodilator FEV(1) responses, and methacholine inhalation challenges in the evaluation of suspected asthma.

@article{Goldstein2001ComparisonsOP,
  title={Comparisons of peak diurnal expiratory flow variation, postbronchodilator FEV(1) responses, and methacholine inhalation challenges in the evaluation of suspected asthma.},
  author={Marc F. Goldstein and Bernadette A Veza and Eliot H. Dunsky and Donald J. Dvorin and George A. Belecanech and I C Haralabatos},
  journal={Chest},
  year={2001},
  volume={119 4},
  pages={1001-10}
}
STUDY OBJECTIVES The validity of peak expiratory flow variation (PEFvar) as defined by National Heart, Lung, and Blood Institute (NHLBI) guidelines as a diagnostic tool for suspected asthma or its comparative value to methacholine inhalation challenge (MIC) or postbronchodilator (BD) FEV(1) responses has not been formally assessed. We prospectively analyzed the correlation of 28 different PEFvar indexes (including 4 NHLBI-compatible indexes) with MIC and pre-BD and post-BD FEV(1) responses in… CONTINUE READING
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