Comparisons of mutation induction by six monocyclic aromatic amines in Salmonella typhimurium tester strains TA97, TA1537, and TA1538.

@article{Shahin1985ComparisonsOM,
  title={Comparisons of mutation induction by six monocyclic aromatic amines in Salmonella typhimurium tester strains TA97, TA1537, and TA1538.},
  author={M. Shahin and C. Chopy and N. Lequesne},
  journal={Environmental mutagenesis},
  year={1985},
  volume={7 4},
  pages={
          535-46
        }
}
The mutagenicity of six monocyclic aromatic amines (2,4-diaminoanisole, 2,4-diaminoethoxybenzene, 2,4-diaminopropoxybenzene, m-phenylenediamine, 2,4-diaminotoluene, and nitro-p-phenylenediamine) was investigated in Salmonella typhimurium strains TA97, TA1537, and TA1538 in the presence of two different amounts of Aroclor 1254-induced S9 preparations. Strain TA1538 was found to be the most responsive of the three strains with this group of compounds. Regarding the other strains, TA1537 responded… 
Base-pair mutation caused by four nitro-group containing aromatic amines in Salmonella typhimurium TA100, TA104, TA4001 and TA4006.
TLDR
The results suggested that the occurrence of histidine revertants was predominantly induced by base-pair (point) mutations and not by suppressor gene mutations.
Mutagenicity of structurally related phenylazo-3-pyridines inSalmonella typhimurium
  • M. Shahin
  • Chemistry, Medicine
    Cell Biology and Toxicology
  • 2004
TLDR
The mutagenicity of phenylazo-3-pyrzdines, like monocyclic aromatic amines and azo dyes, is influenced by the nature of the substifuent chemical groups and their positions in the molecular structure of the compounds.
Studies on the mutagenicity of aniline in association with norharman in the Salmonella/mammalian microscome assay
  • M. Shahin
  • Chemistry, Medicine
    International journal of cosmetic science
  • 1989
TLDR
Mixtures of aniline and norharman were mutagenic in strain TA1538 in the presence of S9 fractions from liver of rats pretreated with Aroclor 1254, and the mutagenicity of the mixture of the two compounds was slight.
Evaluation of new metallized direct dyes for mutagenicity using the Salmonella mammalian mutagenicity assay
A series of new metallized direct dyes based on benzidine congeners, 2,2′-dimethyl-5,5′-dipropoxybenzidine and 5,5′-dipropoxybenzidine, were evaluated for mutagenicity in Salmonella typhimurium
Evaluation of new direct dyes for mutagenicity using the salmonella mammalian mutagenicity assay
A series of new direct dyes based on benzidine congeners, 2,2′-dimethyl-5,5′-dipropoxybenzidine and 5,5′-dipropoxybenzidine, were evaluated for mutagenicity in Salmonella typhimurium strains TA98 and
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References

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Mutagenicity of structurally related aromatic amines in the Salmonella/mammalian microsome test with various S-9 fractions.
  • M. Shahin, C. Chopy, M. Mayet, N. Lequesne
  • Biology, Medicine
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 1983
Relationships between the Chemical Structure and Mutagenic Activity of Monocyclic Aromatic Amines
Hundreds of compounds have now been tested for mutagenic activity in many laboratories throughout the world. Mutagenicity tests are performed to validate a variety of assay systems and to contribute