Comparison of weekly treatment of postmenopausal osteoporosis with alendronate versus risedronate over two years.

@article{Bonnick2006ComparisonOW,
  title={Comparison of weekly treatment of postmenopausal osteoporosis with alendronate versus risedronate over two years.},
  author={Sydney Lou Bonnick and Kenneth G. Saag and Douglas P Kiel and Michael R Mcclung and Marc C. Hochberg and S M Burnett and Anthony I Sebba and Risa Kagan and Erluo Chen and Desmond E. Thompson and Anne E de Papp},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2006},
  volume={91 7},
  pages={2631-7}
}
OBJECTIVE A 1-yr extension of the Fosamax Actonel Comparison Trial was completed to compare changes in bone mineral density (BMD), bone turnover, and upper gastrointestinal tolerability over 2 yr of treatment. DESIGN This was a randomized, double-blind extension conducted at 72 U.S. sites. PATIENTS AND METHODS Of the 1053 women who completed yr 1, 833 postmenopausal women with low BMD entered the extension, continuing their same treatment allocation [once-weekly (OW) alendronate 70 mg or OW… CONTINUE READING
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