Comparison of verapamil and bepridil, two slow channel inhibitors, in protection against calcium-induced arrhythmias

Abstract

Verapamil and bepridil share the common property of antagonizing the slow inward calcium-mediated current, but bepridil has some additional antiarrhythmic properties. The efficacy of these two compounds against CaCl2-induced arrhythmias has been compared in rats. CaCl2 was administered i.v. by continuous infusion until death (25 mg·kg−1·min−1 or 40 mg·kg−1… (More)
DOI: 10.1007/BF00498747

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Cite this paper

@article{CholletDebord1986ComparisonOV, title={Comparison of verapamil and bepridil, two slow channel inhibitors, in protection against calcium-induced arrhythmias}, author={Françoise Chollet-Debord and Nicole Moins and Pierre Gachon and Pierre Duch{\^e}ne-Marullaz}, journal={Naunyn-Schmiedeberg's Archives of Pharmacology}, year={1986}, volume={334}, pages={105-109} }