Comparison of various silica-based monoliths for the analysis of large biomolecules.

Abstract

In the present study, three types of silica-based monoliths, i.e. the first and second generations of commercial silica monolithic columns and a wide-pore prototype monolith were compared for the analysis of large biomolecules. These molecules possess molecular weights between 1 and 66 kDa. The gradient kinetic performance of the first-generation monolith… (More)
DOI: 10.1002/jssc.201300323

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