Comparison of various detection methods for periodontopathic bacteria: can culture be considered the primary reference standard?

@article{Loesche1992ComparisonOV,
  title={Comparison of various detection methods for periodontopathic bacteria: can culture be considered the primary reference standard?},
  author={Walter J. Loesche and Dennis E. Lopatin and Jim Stoll and N van Poperin and Philippe Pierre Hujoel},
  journal={Journal of clinical microbiology},
  year={1992},
  volume={30 2},
  pages={418-26}
}
The development of diagnostic tests for a periodontal infection raises the issue as to what the appropriate reference standard, or "gold standard," should be for the evaluation of a new test. The present research was initiated to compare the ability of several detection methods, i.e., a serial dilution anaerobic culture and/or microscopic procedure, a DNA probe procedure, and immunological reagents using both an enzyme-linked immunosorbent assay and an indirect immunofluorescence assay to… CONTINUE READING

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Microbiological based diagnostic tests for periodontitis. Considerations in regard to sensitivity, specificity and accuracy, p. 417-440

  • W. J. Loesche, P. P. Hujoel
  • 1991

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