Comparison of various antimicrobial agents as catheter lock solutions: preference for ethanol in eradication of coagulase-negative staphylococcal biofilms.

@article{Qu2009ComparisonOV,
  title={Comparison of various antimicrobial agents as catheter lock solutions: preference for ethanol in eradication of coagulase-negative staphylococcal biofilms.},
  author={Yue Qu and Taghrid Istivan and Andrew J. Daley and Duncan A. Rouch and Margaret A. Deighton},
  journal={Journal of medical microbiology},
  year={2009},
  volume={58 Pt 4},
  pages={
          442-50
        }
}
Coagulase-negative staphylococci (CoNS) are the main causative agents of bacteraemia in infants managed in neonatal intensive care units (NICUs). Intraluminal colonization of long-term central venous catheters by these bacteria and subsequent biofilm formation are the prerequisites of the bloodstream infections acquired in NICUs. The catheter lock technique has been used to treat catheter colonization; however, the optimum choice of antimicrobial agents and their corresponding concentrations… CONTINUE READING

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