Comparison of various BCG preparations in the EORTC — ICIG experimental screening for systemic immunity adjuvants applicable to cancer immunotherapy

@article{HallePannenko1976ComparisonOV,
  title={Comparison of various BCG preparations in the EORTC — ICIG experimental screening for systemic immunity adjuvants applicable to cancer immunotherapy},
  author={Olga Halle-Pannenko and Ch. Bourut and M. Kamel},
  journal={Cancer Immunology, Immunotherapy},
  year={1976},
  volume={1},
  pages={17-23}
}
SummaryNine lyophilized, five frozen, and one fresh BCG preparation from various sources were tested for their activity as adjuvants of systemic immunity in mice. Using three tests, the IgM response to sheep red blood cells, immunoprophylaxis of L1210 leukemia, and immunoprophylaxis of Lewis tumor, results consistent with both immunostimulation and immunodepression were observed, varying as a function of the BCG strain, its storage conditions, and the assay used. Only fresh Pasteur strain BCG… CONTINUE READING

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