Comparison of two tourniquet application times for regional intravenous limb perfusions with amikacin in sedated or anesthetized horses.

@article{Aristizbal2016ComparisonOT,
  title={Comparison of two tourniquet application times for regional intravenous limb perfusions with amikacin in sedated or anesthetized horses.},
  author={Fabio Aristiz{\'a}bal and J. C. Estepa Nieto and Alonso Guedes and Julie E. Dechant and Sawsan Z Yamout and Betina Morales and Jane R Snyder},
  journal={Veterinary journal},
  year={2016},
  volume={208},
  pages={
          50-4
        }
}
Regional limb perfusion (RLP) in horses has proven to be a simple and effective technique for the treatment of synovial and musculoskeletal infections in the distal portion of the limbs. The ideal tourniquet time needed to achieve therapeutic synovial concentrations remains unknown. The pharmacokinetic effects of general anesthesia (GA) versus standing sedation (SS) RLP on synovial amikacin concentrations are not completely understood. This study investigated the pharmacokinetic effects of RLP… CONTINUE READING
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