Comparison of two topical preparations for the treatment of onychomycosis: Melaleuca alternifolia (tea tree) oil and clotrimazole.

@article{Buck1994ComparisonOT,
  title={Comparison of two topical preparations for the treatment of onychomycosis: Melaleuca alternifolia (tea tree) oil and clotrimazole.},
  author={David S. Buck and D M Nidorf and J G Addino},
  journal={The Journal of family practice},
  year={1994},
  volume={38 6},
  pages={
          601-5
        }
}
BACKGROUND The prevalence of onychomycosis, the most frequent cause of nail disease, ranges from 2% to 13%. Standard treatments include debridement, topical medications, and systemic therapies. This study assesses the efficacy and tolerability of topical application of 1% clotrimazole solution compared with that of 100% Melaleuca alternifolia (tea tree) oil for the treatment of toenail onychomycosis. METHODS A double-blind, multicenter, randomized controlled trial was performed at two primary… CONTINUE READING

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