Comparison of two dosages of thymoglobulin used as a short-course for induction in kidney transplantation.

@article{Wong2006ComparisonOT,
  title={Comparison of two dosages of thymoglobulin used as a short-course for induction in kidney transplantation.},
  author={Waichi Wong and Neerja Agrawal and M Virginia Pascual and David C Anderson and Hans Hellmuth Hirsch and Kumiko Fujimoto and Francesca Cardarelli and Wolfgang C. Winkelmayer and A. Benedict Cosimi and Nina Tolkoff-Rubin},
  journal={Transplant international : official journal of the European Society for Organ Transplantation},
  year={2006},
  volume={19 8},
  pages={629-35}
}
Thymoglobulin is used effectively as an induction agent in kidney transplantation, but the optimal dose is not well established. We evaluated the degree and durability of T-cell clearances with two different thymoglobulin regimens in adult kidney transplant recipients (KTR). Seven KTR received a 3-day thymoglobulin-based induction of 1.0 mg/kg/day while nine received 1.5 mg/kg/day, in addition to maintenance immunosuppression. Lymphocyte subsets were monitored for 6 months. Renal function… CONTINUE READING